The leading production and consumer state in Latin America, São Paulo boasts the biggest and best infrastructure in Brazil. In a country that depends mostly on road transportation, the quality of roads and the intermodal transport available are key factors in São Paulo's competitive differential. The state’s infrastructure drives its exports.

Multimodal junctions integrate transportation via roads, railways and the waterway system to the ports of Santos and São Sebastião, as well as the Campinas and Guarulhos airports. The Tietê-Paraná Waterway, in addition to linking São Paulo to four other Brazilian states, also transports local products to neighboring companies such as Argentina, Paraguay, Uruguay and Bolivia.

In 2015, the Port of Santos moved 119.9 million tonnes of cargo, the highest level of its history, which is 7.8% bigger than the previous year. A total of 5.144 ships docked in the Port of Santos during that time. Bulk solids account for the most significant portion of the total (49%), followed by general cargo (38%) and bulk liquids (13%). In the northern region of the State, 724.8 tonnes moved through the Port of São Sebastião in 2014, mostly in the form of bulk solids such as sodium carbonate and sodium sulfate.

For both the internal and external markets, the transportation infrastructure guarantees economic indicators that make São Paulo the State with the largest economic potential in Brazil.

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